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Book Description Thoroughly detailed and illustrated, this book examines the construction, properties, applications, and problems associated with specific types of fusion molecules used in clinical and research medicine. The editors present an overview of the field, followed by nine chapters divided into two general sections based on the two primary parts of the antibody molecule: Fab fusion proteins and Fc fusion proteins. In addition, numerous renowned scientists in the field have... >> |
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Molecular Cancer Therapeutics : Strategies for Drug Discovery and Development |
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From the New England Journal of Medicine, January 27, 2005 In this excellent and timely book, George Prendergast has created a primer for academically trained laboratory scientists about the challenges of developing modern drugs. The growing expectation among the public that scientific advances in cancer research should be applied to clinical medicine as rapidly as possible has made it essential for even the most basic-science-oriented researcher to gain some familiarity with how dr... >> |
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Signaling Networks and Cell Cycle Control : The Molecular Basis of Cancer and Other Diseases (Cancer Drug Discovery and Development, 5) |
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From Book News, Inc. Summarizes recent knowledge in the field and describes the effort to design and synthesize inhibiting molecules and to evaluate their biochemical and biological activities. Reviews relevant cell surface receptors, their ligands, and their downstream pathways, and examines the latest findings on components of novel signaling networks which control the activity of nuclear transcription factors and cell-cycle- regulatory molecules. Emphasis is on the most likely m... >> |
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Oncology
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