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Probability Models for DNA Sequence Evolution |
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Book Description
Our basic question is: Given a collection of DNA sequences, what underlying forces are responsible for the observed patterns of variability? To approach this question we introduce and analyze a number of probability models: the Wright-Fisher model, the coalescent, the infinite alleles model, and the infinite sites model. We study the complications that come from nonconstant population size, recombination, population subdivision, and three forms of natural selection:... >> |
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Understanding DNA : The Molecule and How it Works |
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From Book News, Inc.
A clear and easy-to-read presentation of the way DNA works at a molecular level--for use as a supplementary text in an undergraduate biochemistry course, a main text for a course in DNA structure, or an approachable introduction for generally educated readers who want to know more about the fundamental processes of life. Annotation copyright Book News, Inc. Portland, Or.--This text refers to the
Model Organisms in Drug Discovery |
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From Book News, Inc.
Yeast, nematodes, fruit flies, zebrafish, and mice are all used by scientists as model organisms for studying drug reactions and most have the advantages of complete genome sequences and "forward" and "reverse" genetic tools for genome-wide functional discoveries. Carroll and Fitzgerald (applied genomics, Pharmaceutical Research Institute, Bristol-Myers Squibb) present a text that describes the technical advantages for each of these organisms in turn, as well a... >> |
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Genetics
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