Release Date: November, 1992
Paperback
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From Book News, Inc.
Explores the design of new drugs in light of three-dimensional images of biological molecules on the atomic level, which are now possible. The eight chapters are independent, but form a progression from the role of macromolecules in drug action, through the physicochemical principles and computational techniques of designing small chemicals, to experimental studies illustrating the successes and increased knowledge, and an overview of how molecular tailoring complements other approaches to selecting chemicals as medicine. Annotation copyright Book News, Inc. Portland, Or.
The publisher, John Wiley & Sons
Using a practical approach, it describes the concept of matching drugs to target molecules and details how this can be simulated using computer/graphical representations. Leading experts in their fields contribute important articles regarding this topic. Designed as a state-of-the-art book, it concludes with a discussion of the future of such design. Rating
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