Release Date: 15 January, 1995
Hardcover
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From Book News, Inc.
Arising from the 1994 Nobel symposium in Stockholm, Sweden, this volume on genomic or parental imprinting encompasses clinical genetics, pathology, developmental biology, evolution, and genetics. It helps to explain not only the mechanisms of genomic imprinting, but also its biological and medical consequences. The 24 contributions are organized in six sections: genomic imprinting in mammals; chromatin structure and DNA modifications; mechanisms of imprinting; genomic imprinting in embryonal tumors and overgrowth disorders; genomic imprinting and the Prader-Willi syndrome; and imprinting--a search for new genes and unifying principles. Annotation c. by Book News, Inc., Portland, Or.
Review
"The names of most of the contributors will be familiar to those who have followed the field, as will the subject matter of most of the papers. But this is unlikely to prevent the vast majority of readers from encountering a number of pleasant surprises...a major strength of this collection, for the student and the casually interested reader, is in the way the majority of contributors have summarized the results of many experiments in a few sentences...The conversational tone of the contributions further makes for entertaining reading." Carmen Sapienza, Science "The 24 contributed chapters have considerable scope...a useful resource not only for those actually working in the area, but also for those who are not working in this field but who need to maintain some level of knowledge for educational purposes." Roger W. Melvold, Doody's Health Sciences Book Review Journal "...a valuable resource....It should be useful to scientists new to the field and to those wanting a broad view of the various imprinted systems....the information and models that it contains will continue to guide research in this dynamic field." Fay L. Shamanski, American Journal of Human Genetics
Book Description
Genomic imprinting results in the preferential expression of one gene, depending on the parent of origin, and it is associated with several disease syndromes in humans. This book covers a wealth of research material on chromatin structure, epigenetics, clinical genetics, developmental biology, cancer, hypotheses of evolution, and the molecular basis of the imprinting process, which will help explain not only the mechanisms of genomic imprinting, but also its biological and medical consequences.
Book Info
Genetic research on genomic or parental imprinting which results in the preferential expression of one allele. Based on the 1994 Nobel Symposium, otherwise unidentified. 68 contributors, 22 U.S. Rating
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