From Book News, Inc.
Strachan (scientific director, Institute for Human Genetics; human molecular genetics, University of Newcastle, UK) and Read (human genetics, Manchester University) have integrated the latest data from the Human Genome Project and have included new chapters on cells and development and on functional genomics, proteomics, and bioinformatics in this third edition of a text bridging elementary textbooks and the research literature. There is rewritten and reorganized coverage of complex disease genetics, and increased emphasis on gene function and on applications of genetic knowledge and ethical issues. Material is written so that those with relatively little background can appreciate the latest research.Copyright © 2004 Book News, Inc., Portland, OR
Journal of Medical Genetics, 2004, #41
"…Timely, up to date, and has enormous and comprehensive coverage… …This book is a good buy, an excellent read..."
Book Description
Following the completion of the Human Genome Project the content and organization of the third edition of Human Molecular Genetics (HMG) has been thoroughly revised. PART ONE (CHAPTERS 1-7) covers basic material on DNA structure and function, chromosomes, cells and development, pedigree analysis and the basic techniques used in the laboratory. PART TWO (CHAPTERS 8-12) discusses the various genome sequencing projects and the insights they provide into the organization, expression, variation and evolution of our genome. PART THREE (CHAPTERS 13-18) focuses on mapping, identifying and diagnosing the genetic causes of mendelian and complex diseases and cancer. PART FOUR (CHAPTERS (19-21) looks at the wider horizons of functional genomics, proteomics, bioinformatics, animal models and therapy. There are new chapters on cells and development and on functional genomics. The sections on complex diseases have been completely rewritten and reorganized, as has the chapter on Genome Projects. Other changes include a new section on molecular phylogenetics (Chapter 12) and the introduction of ‘Ethics Boxes’ to discuss some of the implications of the new knowledge. Virtually every page has been revised and updated to take account of the stunning developments of the past four years since the publication of the last edition of Human Molecular Genetics.
Book Info
Univ. of Newcastle, UK. Textbook focuses on the new knowledge in human molecular genetics since the Human Genome Project. Includes new chapters on cells and development and on functional genomics, proteomics, and bioinformatics. Emphasis is placed on gene function and on applications of genetic knowledge, including ethical issues. Previous edition: c1999.
The publisher, John Wiley & Sons
A complete, up-to-the-minute account of human molecular genetics from basic principles to current practice. Designed to engage and motivate students the text covers the organization, expression and evolution of the human genome. Features a comprehensive chapter on the latest progress in the Human Genome Project.--This text refers to an out of print or unavailable edition of this title. Rating 5.0
The book to read for an in-depth backgroundThis book is a very complete overview of molecular biology as applied to human genetics. As someone interested in bioinformatics and computational biology, I read it to get a background in the biology/genetics behind these fields. That being said, I was glad I made the choice of this book as the authors do a fine job of explaining the relevant concepts and biological processes in genetics. In the light of the recent draft of the human genome, this edition of the book is especially timely. That being said, there is a lot of material covered, and to digest all of the terms and processes outlined takes a fair amount of time. The discussion on functional genomics and the post-genome sequencing era was particularly interesting. More could be said on gene sequencing validation as it applies to gene therapies and drug discovery. The most fascinating chapter was the one on genetic manipulation of animals as this is where genetic engineering has had its successful proving ground. Even though this is a science text, a discussion on the ethics of human genetic engineering would be appropriate, given some of the current attitudes about it. My opinion is that these technologies should move ahead with diligence; humankind cannot afford not to do so. I would highly recommend this book to those who have the time to read through it, as it offers the necessary concepts needed to understand this fascinating area. This is a good book in studying human geneticsThis is a good book in studying genetics referring human molecular genetics. I can examine myself with it.Whwn you finish reading Molecular biology of the CELL, you can understand genetics. So, this book and the book,Human Molecular genetics, are very helpful in studying genetics.An excellent text! For undergrad and grad students.Very comprehensive reading. It sure gives the reader a thorough explanation of the concept. Each chapter provides clear, yet detailed illustrations. Further explanations are given on several key concepts by including "highlights" for a particular topic. Although this book tackles more general knowledge on human genetics, it sure is highly recommended to students or professionals starting to learn Human Genetics. |
